Gene-dense autosomal chromosomes show evidence for increased selection

摘要

LDU maps of chromosome 22 for three populations. The cumulative LDU scale is plotted against the physical location in kilobases for three populations. Map contours show close alignment across populations between steeper areas of rapid LD breakdown and flatter regions of strong LD. Map lengths reflect differences in effective bottleneck times between populations with a longer time to an effective bottleneck for the African Baganda and Ethiopian populations compared to the Wellderly sample of European origin