首页> 美国卫生研究院文献>Data in Brief >Dataset on the effect of Benzene exposure on genetic damage hematotoxicity telomere length and polymorphisms in metabolic and DNA repair genes
【2h】

Dataset on the effect of Benzene exposure on genetic damage hematotoxicity telomere length and polymorphisms in metabolic and DNA repair genes

机译:基于苯暴露对遗传损伤血液毒性端粒长度和多态性的基因分子代谢和DNA修复基因

代理获取
本网站仅为用户提供外文OA文献查询和代理获取服务,本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文,但由于OA文献来源多样且变更频繁,仍可能出现获取不到、文献不完整或与标题不符等情况,如果获取不到我们将提供退款服务。请知悉。

摘要

In this paper, we present an occupational dataset to evaluate benzene exposure on the effective biomarkers of genetic damage, indicated as cytokinesis-block micronucleus (MN) frequency, hematotoxicity, indicated as white blood cells (WBC) counts, and molecular marker of telomere length (TL). And we further to eliminate the mechanism of benzene induced damage. Then evaluate the effects of sites polymorphism in environmental response genes, including 18 sites in metabolic and DNA repair genes, and the interaction between gene polymorphism and benzene exposure. This dataset is supplementary to the submitted research by [1] focused on the biomarkers TL, and a detailed description of the subjects sampling, biomarkers detection, data analysis and discussion are discussed in detail.
机译:在本文中,我们提出了职业数据集,以评估苯暴露于遗传损伤的有效生物标志物上,表示为细胞因子阻断微核(Mn)频率,血液毒性,表示为白细胞(WBC)计数和端粒长度的分子标记。 (TL)。我们进一步消除苯致损伤的机制。然后评估位点多态性在环境响应基因中的影响,包括18个代谢和DNA修复基因的位点,以及基因多态性与苯暴露之间的相互作用。该数据集补充了[1]的提交的研究,其专注于生物标志物TL,并详细讨论了对象采样,生物标志物检测,数据分析和讨论的对象的描述。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
代理获取

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号