Comment on Effectiveness of 190 µg Fluocinolone Acetonide versus 700 µg Dexamethasone Intravitreal Implants in Diabetic Macular Edema Using the Area-Under-the-Curve Method: The CONSTANT Analysis Response to Letter

摘要

With interest, we read the letter to the Editor regarding the Effectiveness of 190 μg fluocinolone acetonide versus 700 μg dexamethasone intravitreal implants in diabetic macular edema using the area-under-the-curve method: The CONSTANT analysis by Stewart and Taylor published in Clinical Ophthalmology. The key concerns raised by the authors relate to the design deficiencies of the MEAD studies1 and highlight two specific issues – the six month dosing of the dexamethasone implant and the potentially delayed removal of cataracts.