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Necrotic leg ulcers associated with krokodil injection in a 41-year-old man

机译:在一个41岁的男人中与krokodil注射相关的坏死腿部溃疡

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摘要

A 41-year-old man was admitted to hospital with painful necrotic leg ulcers (Figure 1). He exhibited narcotic-seeking behaviour, such as requesting narcotics daily, refusing non-narcotic analgesia and hiding narcotics, but he denied using injection drugs. The patient’s ulcers were irregular, with a peculiar black scale on the intact skin. Skin biopsy showed an extensive ulcer with neutrophilic inflammation, and heavy growth of Proteus vulgaris and Morganella morganii was seen on tissue culture. Our presumptive diagnosis was pyoderma gangrenosum with secondary infection. We prescribed prednisone, wound care and antibiotics, and our patient’s lesions began to improve. At the same time, we managed his opioid withdrawal symptoms. About a month into our patient’s stay in hospital, we learned from his roommate and family that he had been injecting a synthetic morphine derivative known as krokodil.
机译:一个41岁的男子被患有痛苦的坏死腿部溃疡的医院录取(图1)。他展出了寻求麻醉品的行为,例如请求麻醉药,拒绝非麻醉镇痛和隐藏麻醉品,但他否认使用注射药物。患者的溃疡是不规则的,在完整的皮肤上具有特殊的黑色尺度。皮肤活组织检查显示出具有嗜中性炎症的广泛溃疡,并且在组织培养上观察到蛋白质和莫加尔菌菌和Morganella Morganii的重量率。我们推测的诊断是具有继发感染的pyoderma gangrenosum。我们规定了泼尼松,伤口护理和抗生素,我们的病人的病变开始改善。与此同时,我们管理他的阿片类药物戒断症状。我们患者入住医院大约一个月,我们从他的室友和家庭中学到,他一直注射称为krokokodil的合成吗啡衍生物。

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