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Network pharmacology and molecular docking analyses on Lianhua Qingwen capsule indicate Akt1 is a potential target to treat and prevent COVID‐19

机译：莲花清温胶囊的网络药理学和分子对接分析表明AKT1是治疗和预防Covid-19的潜在目标

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摘要

Coronavirus disease 2019 (COVID‐19) is rapidly spreading worldwide. Lianhua Qingwen capsule (LQC) has shown therapeutic effects in patients with COVID‐19. This study is aimed to discover its molecular mechanism and provide potential drug targets.

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期刊名称 Cell Proliferation
作者
Qi‐Dong Xia; Yang Xun; Jun‐Lin Lu; Yu‐Chao Lu; Yuan‐Yuan Yang; Peng Zhou; Jia Hu; Cong Li; Shao‐Gang Wang;
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作者单位

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年(卷),期 2020(53),12
年度 2020
页码 e12949
总页数 13
原文格式 PDF
正文语种
中图分类细胞生物学;
关键词
Akt1; Chinese patent medicine; COVID‐19; Lianhua Qingwen capsule; molecular docking; network pharmacology;

机译：AKT1;中国专利医学;Covid-19;连华清温胶囊;分子对接;网络药理学;

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1. Exploration on Shufeng Jiedu Capsule for Treatment of COVID-19 Based on Network Pharmacology and Molecular Docking [J] . Yanwu Zhao, Junhui Hu, Jiang Song, Chinese Medicine . 2020,第1期

机译：基于网络药理学和分子对接的基于网络药理学和分子对接治疗Covid-19治疗的疏峰Jiedu胶囊探索
2. Exploration on Shufeng Jiedu Capsule for Treatment of COVID-19 Based on Network Pharmacology and Molecular Docking [J] . Yanwu Zhao, Junhui Hu, Jiang Song, 中医（英文） . 2020,第001期

机译：基于网络药理和分子对接的疏风解毒胶囊治疗COVID-19的探索
3. The active ingredients of Huanglian Jiedu Decoction in treating COVID-19 based on network pharmacology, molecular docking and molecular dynamics simulation [J] . Ping Xie, Xiaohan Jin, Yuanfa Lai, TMR Modern Herbal Medicine . 2021,第1期

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4. Establishing a Novel In Vivo Platform to Interrogate the Effects of Pharmacologic and Molecularly Targeted Modulation of CDK5 in the Invasive and Metastatic Potential of Medulloblastoma in Live Experimental Animals [C] . A. Petrosiute, J. Myers, J. Nthale, International Metallographic Society Annual meeting;Microscopy Society of America Annual Meeting;Microanalysis Society Annual meeting . 2011

机译：建立一个新颖的体内平台，以询问药理学和分子靶向调节CDK5在活实验动物的髓母细胞瘤侵袭和转移潜能中的作用
5. Molecular mechanisms defining G-protein betagamma subunit recognition and regulation of target molecules: Potential of Gbetagamma as a pharmacological target. [D] . Bonacci, Tabetha M. 2006

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6. Network pharmacology and molecular docking analysis on molecular targets andmechanisms of Huashi Baidu formula in the treatment of COVID-19 [O] . Quyuan Tao, Jiaxin Du, Xiantao Li, -1

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7. Potential mechanism prediction of Cold-Damp Plague Formula against COVID-19 via network pharmacology analysis and molecular docking [O] . Lin Han, Xiu-Xiu Wei, Yu-Jiao Zheng, 2020

机译：通过网络药理学分析和分子对接对Covid-19冷水损伤公式的潜在机制预测

Network pharmacology and molecular docking analyses on Lianhua Qingwen capsule indicate Akt1 is a potential target to treat and prevent COVID‐19

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