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Characteristics and Clinical Outcomes of Adult Patients Hospitalized with COVID-19 — Georgia March 2020

机译:Covid-19住院患者的成人患者特征和临床结果 - 格鲁吉亚3月20日

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摘要

SARS-CoV-2, the novel coronavirus that causes coronavirus disease 2019 (COVID-19), was first detected in the United States during January 2020 (1). Since then, >980,000 cases have been reported in the United States, including >55,000 associated deaths as of April 28, 2020 (2). Detailed data on demographic characteristics, underlying medical conditions, and clinical outcomes for persons hospitalized with COVID-19 are needed to inform prevention strategies and community-specific intervention messages. For this report, CDC, the Georgia Department of Public Health, and eight Georgia hospitals (seven in metropolitan Atlanta and one in southern Georgia) summarized medical record–abstracted data for hospitalized adult patients with laboratory-confirmed* COVID-19 who were admitted during March 2020. Among 305 hospitalized patients with COVID-19, 61.6% were aged <65 years, 50.5% were female, and 83.2% with known race/ethnicity were non-Hispanic black (black). Over a quarter of patients (26.2%) did not have conditions thought to put them at higher risk for severe disease, including being aged ≥65 years. The proportion of hospitalized patients who were black was higher than expected based on overall hospital admissions. In an adjusted time-to-event analysis, black patients were not more likely than were nonblack patients to receive invasive mechanical ventilation† (IMV) or to die during hospitalization (hazard ratio [HR] = 0.63; 95% confidence interval [CI] = 0.35–1.13). Given the overrepresentation of black patients within this hospitalized cohort, it is important for public health officials to ensure that prevention activities prioritize communities and racial/ethnic groups most affected by COVID-19. Clinicians and public officials should be aware that all adults, regardless of underlying conditions or age, are at risk for serious illness from COVID-19.
机译:SARS-COV-2,这是导致冠状病毒疾病2019(Covid-19)的新型冠状病毒,于2019年1月20日(1)中首次在美国检测到。从那时起,美国报告了980,000例,其中包括> 55,000名相关死亡,截至2020年4月28日(2)。需要与Covid-19住院的人口特征,潜在的医疗条件和临床结果的详细数据,以告知预防策略和特定于社区的干预信息。对于本报告,CDC,佐治亚州公共卫生部和八个格鲁吉亚医院(七分之一的亚特兰大和南方南部的七)概述了医疗记录抽象的住院成年人患者的数据确认* Covid-19在内2020年3月20日。在305名住院治疗患者中,61.6%令人患者<65岁,50.5%是女性,其中83.2%,已知种族/种族是非西班牙裔(黑色)。四分之一的患者(26.2%)没有思想将它们处于严重疾病的风险较高的情况下,包括≥65岁。基于整体医院入学的人的住院患者的比例高于预期。在调整后的时间分析中,黑人患者不太可能比非黑皮患者接受侵入力机械通气†(IMV)或在住院期间死亡(危险比[HR] = 0.63; 95%置信区间[CI] = 0.35-1.13)。鉴于这种住院队列内的黑人患者的超额陈述,公共卫生官员非常重要,以确保预防活动优先考虑受Covid-19最受影响的社区和种族/族群。临床医生和公共官员应该意识到所有成年人,无论潜在的条件或年龄,来自Covid-19的严重疾病风险。

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