Atorvastatin in Combination with Pegylated Interferon and Ribavirin Provided High Rate of Sustained Virological Response in Patients with Genotype 3 Hepatitis C Virus

机译：阿托伐他汀与聚乙二醇化干扰素和利巴韦林联用可为3型丙型肝炎病毒患者提供较高的持续病毒学应答

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BACKGROUND:Chronic hepatitis C virus infection represents a more frequent cause of liver cirrhosis and hepatocellular carcinoma. Statins, inhibit HCV replication in vitro, enhance the antiviral effect of the already known antiviral drugs and reduce their resistance.

机译：背景：慢性丙型肝炎病毒感染是肝硬化和肝细胞癌的更常见原因。他汀类药物在体外抑制HCV复制，增强已知抗病毒药物的抗病毒作用并降低其耐药性。

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期刊名称 Open Access Macedonian Journal of Medical Sciences
作者
Beti Todorovska; Viktorija Caloska-Ivanova; Magdalena Dimitrova-Genadieva; Meri Trajkovska; Rozalinda Popova-Jovanovska; Kalina Grivceva-Stardelova; Fana Licoska-Josifovic; Vladimir Andreevski; Elena Curakova-Ristovska; Nenad Joksimovic;
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年(卷),期 2019(7),10
年度 2019
页码 1641–1648
总页数 8
原文格式 PDF
正文语种
中图分类
关键词
Hepatitis C virus infection Statins Pegylated interferon alpha Ribavirin Sustained virological response;

机译：丙型肝炎病毒感染;他汀类药物;聚乙二醇化干扰素α;利巴韦林;持续的病毒学应答;

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专利

1. Rapid virological response in peripheral blood mononuclear cells with an increase of hepatitis C virus-specific interferon-gamma production predisposes to sustained virological response in patients with chronic hepatitis C genotype 1 undergoing treatment with pegylated-interferon alpha 2a plus ribavirin. [J] . Perrella A, Sbreglia C, Atripaldi L, Scandinavian journal of gastroenterology. . 2010,第2期

机译：丙型肝炎病毒基因型1型慢性丙型肝炎患者接受聚乙二醇化干扰素α2a加利巴韦林治疗后，外周血单核细胞快速的病毒学应答会随丙型肝炎病毒特异性干扰素-γ产生的增加而产生持续的病毒学应答。
2. A 24-week treatment strategy with pegylated interferon/ribavirin in HIV/hepatitis C virus genotype 3-coinfected patients who achieved a rapid virologic response results in a high sustained virologic response rate [J] . Rivero-JuarezA., López-CortésL.F., CamachoA., Clinical infectious diseases . 2014,第1期

机译：HIV /丙型肝炎病毒基因型3合并感染患者的聚乙二醇干扰素/利巴韦林24周治疗策略获得了快速的病毒学应答，导致持续的病毒学应答率高
3. Rapid virological response assessment by Abbott RealTime hepatitis C virus assay for predicting sustained virological responses in patients with hepatitis C virus genotype 1 treated with pegylated-interferon and ribavirin [J] . Pei-yuan Su, Hsu-Heng Yen, Yu-Chun Hsu, Kaohsiung Journal of Medical Sciences . 2016,第7期

机译：通过雅培实时丙型肝炎病毒测定进行快速病毒学应答评估，以预测聚乙二醇化干扰素和利巴韦林治疗的基因型1型丙型肝炎患者的持续病毒学应答
4. Predictability of Sustained Virological Response (SVR) in Patients with HCV/HIV Co-infection During Combination Therapy With Peginterferon Alfa-2A (40KD) (PEGASYS~R) Plus Ribavirin (COPEGUS~R) in the APRICOT Trial [C] . M. Rodriguez Torres, F.J. Torriani, E. Lissen International AIDS Conference . 2004

机译：HCV / HIV与Peginterferon Alfa-2a（40KD）（Pegasys〜R）加上利韦韦林（Copegus〜R）在杏试验期间HCV / HIV CONOMENT患者持续病毒学反应（SVR）的可预测性
5. The meaning of adherence among veterans receiving pegylated interferon and ribavirin antiviral treatment for chronic hepatitis C. [D] . Phillips, Frances Hinshaw. 2011

机译：接受聚乙二醇干扰素和利巴韦林抗病毒治疗的慢性丙型肝炎退伍军人依从性的含义。
6. Predictors of sustained virological response to a 48-week course of pegylated interferon alfa-2a and ribavirin in patients infected with hepatitis C virus genotype 4 [O] . Hamad Al Ashgar, Ahmed Helmy, Mohamed Q. Khan, 2009

机译：预测感染丙型肝炎病毒基因型4的患者对聚乙二醇化干扰素α-2a和利巴韦林48周疗程的持续病毒学应答
7. Atorvastatin in Combination with Pegylated Interferon and Ribavirin Provided High Rate of Sustained Virological Response in Patients with Genotype 3 Hepatitis C Virus [O] . Beti Todorovska, Viktorija Caloska-Ivanova, Magdalena Dimitrova-Genadieva, 2019

机译：阿托伐他汀与聚乙二醇化干扰素和利巴韦林组合提供了高患者基因型3丙型肝炎病毒的持续持续病毒学反应率高

Atorvastatin in Combination with Pegylated Interferon and Ribavirin Provided High Rate of Sustained Virological Response in Patients with Genotype 3 Hepatitis C Virus

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