Capacity of Infusion Lines for Insulin Adsorption: Effect of Flow Rate on Total Adsorption

摘要

Insulin adsorption to clinical materials has been well observed, but not well quantified. Insulin adsorption reduces expected and actual insulin delivery and is unaccounted for in insulin therapy or glycemic control. It may thus contribute to poor control and high glycemic variability. This research quantifies the problem in the context of clinical use.