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Left main bifurcation stenting: the impact of strut thickness on long-term outcomes

机译:左主分叉支架:支柱厚度对长期结果的影响

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摘要

Over the latest years, both randomized controlled trials (RCTs) and observational studies have provided solid basis for percutaneous coronary intervention as a treatment option for unprotected left main (LM) bifurcation coronary artery disease. A recent meta-analysis comparing the long-term outcome between LM bifurcation disease one-stent technique versus two-stent technique, the study has demonstrated that one-stent strategy resulted associated with both major adverse cardiac events and target lesion revascularizations (TLRs) lower rates but resulted equivalent to two-stent strategy in terms of cardiovascular mortality, target lesion failure and stent thrombosis (ST) even at one-year and three-year follow-up.[1] However, previous analyses have mainly focused on the type of double stent strategy adopted, as well as bifurcation geometrical properties (i.e., bifurcation angle, side branch length, and etc) or different biodegradable polymer. On the contrary, the impact of stents strut thickness has been generally neglected in current literature.
机译:在最新年中,随机对照试验(RCT)和观察性研究都为经皮冠状动脉干预提供了坚实的基础,作为未受保护的左主(LM)分叉冠状动脉疾病的治疗选择。最近的荟萃分析比较了LM分岔疾病的长期结果,单支架技术与双支架技术相比,这项研究表明,一支支架策略导致与主要不良心脏事件和靶病变血运重建(TLRS)降低相关速率,但导致在心血管死亡率,目标病变失败和支架血栓形成(ST)中的两支支架策略,即使在一年和三年的随访中也是如此。[1]然而,之前的分析主要集中在采用的双支架策略类型,以及分叉几何特性(即分叉角度,侧分支长度等)或不同的可生物降解聚合物。相反,支架支柱厚度的影响在当前的文献中一般忽略。

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