首页> 美国卫生研究院文献>Journal of Enzyme Inhibition and Medicinal Chemistry >Novel chalcone/aryl carboximidamide hybrids as potent anti-inflammatory via inhibition of prostaglandin E2 and inducible NO synthase activities: design synthesis molecular docking studies and ADMET prediction

【2h】

Novel chalcone/aryl carboximidamide hybrids as potent anti-inflammatory via inhibition of prostaglandin E2 and inducible NO synthase activities: design synthesis molecular docking studies and ADMET prediction

机译：新型Chalcone /芳基羧酰亚胺酰胺杂交剂作为效力抗炎通过抑制前列腺素E2和诱导型无合成酶活性：设计合成分子对接研究和呼吸预测

代理获取

本网站仅为用户提供外文OA文献查询和代理获取服务，本网站没有原文。下单后我们将采用程序或人工为您竭诚获取高质量的原文，但由于OA文献来源多样且变更频繁，仍可能出现获取不到、文献不完整或与标题不符等情况，如果获取不到我们将提供退款服务。请知悉。

页面导航

著录项
相似文献
相关主题

著录项

期刊名称 Journal of Enzyme Inhibition and Medicinal Chemistry
作者
Tarek S. Ibrahim; Amr H. Moustafa; Ahmad J. Almalki; Rasha M. Allam; Abdulhamid Althagafi; Shadab Md; Mamdouh F. A. Mohamed;
展开▼
作者单位

展开▼
年(卷),期 2021(36),1
年度 2021
页码 1067–1078
总页数 12
原文格式 PDF
正文语种
中图分类分子生物学;药物化学;
关键词
Chalcone; carboximidamide; iNOS inhibitors; anti-inflammatory; amidoxime; PGE2;

机译：Chalcone;羧纤维酰胺;INOS抑制剂;抗炎;amidoxime;PGE2;

相似文献

外文文献
中文文献
专利

1. SYNTHESIS, INSILICO DOCKING AND ADMET STUDIES OF ARYL ACETIC ACID DERIVATIVES AS PROSTAGLANDIN ENDOPEROXIDE H SYNTHASE-2 INHIBITORS [J] . Abirami Kandhaswamy, Saravanan Rangan, Irshad Ahmed, Asian Journal of Pharmaceutical and Clinical Research . 2017,第4期

机译：内酯类内毒素H SYNTHase-2抑制剂前列腺素芳基乙酸衍生物的合成，硅酮对接和修饰研究
2. Structural characterization, DFT calculations, ADMET studies, antibiotic potentiating activity, evaluation of efflux pump inhibition and molecular docking of chalcone (E)-1-(2-hydroxy-3,4,6-trimethoxyphenyl)-3-(4-methoxyphenyl)prop-2-en-1-one [J] . Xavier Jayze da Cunha, de Queiroz Almeida-Neto Francisco Wagner, da Silva Priscila Teixeira, Journal of Molecular Structure . 2021,第1期

机译：结构表征，DFT计算，呼吸探测，抗生素增强活性，脱铝酮泵抑制和分子对接的评价（e）-1-（2-羟基-3,4,6-三甲氧基苯基）-3-（4-甲氧基苯基） Prop-2-en-1-one
3. A novel structural class of coumarin-chalcone fibrates as PPARα/γ agonists with potent antioxidant activities: Design, synthesis, biological evaluation and molecular docking studies [J] . Handong Niu, Wenbao Wang, Jinyan Li, European Journal of Medicinal Chemistry: Chimie Therapeutique . 2017,第期

机译：一种新型结构类别的CoMarin-Chalcone纤维，与有效的抗氧化活性的PPARα/γ激动剂：设计，合成，生物学评估和分子对接研究
4. Synthesis, In Silico Molecular Docking Modeling and Pharmacophore Mapping of (E)-3-(4-Hydroxy-2,6-Dimethoxyphenyl)-1 -Phenylprop-2-en-1 - One as Potential New Inhibitor of Microsomal Prostaglandin E2 Synthase-1 [C] . Pitipat Sanphetchaloemchok, Mohd Fadhlizil Fasihi Mohd Aluwi, Kamal Rullah, Postgraduate Symposium on Industrial Science and Technology . 2020

机译：（E）-3-（4-羟基-2,6-二甲氧基苯基）-1-phenylprop-2-en-1的硅分子对接建模和药效线映射，作为微粒体前列腺素E2合酶的潜在新抑制剂 - 1
5. Progress toward the synthesis of a biomimetic membrane, and, The study of cadmium sulfide Qdots: A possible photocatalyst for both the efficient reduction of aryl azides and the rational design of molecular-scale patterned surfaces. [D] . Gano, Kyle William. 2000

机译：仿生膜合成的进展，以及硫化镉Qdots的研究：有效还原芳基叠氮化物和合理设计分子尺度图案化表面的可能的光催化剂。
6. Hybrid caffeic acid derivatives as monoamine oxidases inhibitors: synthesis radical scavenging activity molecular docking studies and in silico ADMET analysis [O] . Priyanka Dhiman, Neelam Malik, Anurag Khatkar 2018

机译：杂化咖啡酸衍生物作为单胺氧化酶抑制剂：合成自由基清除活性分子对接研究和计算机模拟ADMET分析
7. SYNTHESIS, INSILICO DOCKING AND ADMET STUDIES OF ARYL ACETIC ACID DERIVATIVES AS PROSTAGLANDIN ENDOPEROXIDE H SYNTHASE-2 INHIBITORS [O] . Abirami Kandhaswamy, Saravanan Rangan, Irshad Ahmed, 2017

机译：芳基乙酸衍生物作为前列腺素内转油氧化物H合酶-2抑制剂的合成，Insilico对接和呼吸探服和呼吸研究

Novel chalcone/aryl carboximidamide hybrids as potent anti-inflammatory via inhibition of prostaglandin E2 and inducible NO synthase activities: design synthesis molecular docking studies and ADMET prediction

著录项

相似文献

相关主题

期刊订阅