Oral giant cell fibroma: A report of three cases

摘要

Histopathological microphotographs of our three cases of oral giant cell fibroma (GCF) on the buccal mucosae of three middle-aged male patients, respectively. (A and B) Low-power (A) and high-power (B) microphotographs of the first GCF case showing a fibrous mass covered by hyperparakeratotic stratified squamous epithelium with elongated and pointed rete ridges. There were mononuclear or binuclear stellate giant fibroblasts dispersed in the subepithelial fibrous connective tissues. (C and D) Low-power (C) and high-power (D) microphotographs of the second GCF case exhibiting similar histopathological features to the first GCF case except that the GCF was covered by hyperorthokeratotic stratified squamous epithelium. (E and F) Low-power (E) and high-power (F) microphotographs of the third GCF case demonstrating similar histopathological features to the second GCF case except that a trinuclear stellate giant fibroblast was discovered in the subepithelial fibrous connective tissue (pointed by the black arrow) (Hematoxylin and eosin stain; original magnification; A, C, and E, 4 × ; B, D, and F, 40 × ).