Liquid Diagnosis of Hepatic Encephalopathy: Are We There Already?

摘要

Hepatic encephalopathy (HE) is a neurocognitive syndrome associated with liver disease and/or portosystemic shunts. Its diagnosis is clinical and requires exclusion of many other conditions that can present with similar neuropsychiatric abnormalities [1]. The broad differential diagnosis, and huge clinical overlap with many metabolic, neurologic and psychiatric disorders, is a challenge for clinicians that must decide in which patients further laboratorial, imaging and neurophysiological investigation is warranted.