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Acute Care of Older Patients with COVID-19: Clinical Characteristics and Outcomes

机译:Covid-19患者的急性护理:临床特征和结果

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摘要

(1) Background: COVID-19 has become a global pandemic and older patients present higher mortality rates. However, studies on the characteristics of this population set are limited. The objective of this study is to describe clinical characteristics and outcomes of older patients hospitalized with COVID-19. (2) Methods: This retrospective cohort study was conducted from March to May 2020 and took place in three acute geriatric wards in France. Older patients hospitalized for COVID-19 infections were included. We collected clinical, radiological, and laboratory outcomes. (3) Results: Ninety-four patients were hospitalized and included in the final analysis. Mean age was 85.5 years and 55% were female. Sixty-four (68%) patients were confirmed COVID-19 cases and 30 (32%) were probable. A majority of patients were dependent (77%), 45% were malnourished, and the mean number of comorbidities was high in accordance with the CIRS-G score (12.3 ± 25.6). The leading causes of hospitalization were fever (30%), dyspnea (28%), and geriatric syndromes (falls, delirium, malaise) (18%). Upon follow-up, 32% presented acute respiratory failure and 30% a geriatric complication. Frailty and geriatric characteristics were not correlated with mortality. Acute respiratory failure (p = 0.03) and lymphopenia (p = 0.02) were significantly associated with mortality. (4) Conclusions: Among older patients hospitalized with COVID-19, clinical presentations were frequently atypical and complications occurred frequently. Frailty and geriatric characteristics were not correlated with mortality.
机译:(1)背景:Covid-19已成为全球性大流行和老年患者的死亡率较高。然而,对该人口集的特征的研究有限。本研究的目的是描述与Covid-19住院的老年患者的临床特征和结果。 (2)方法:此回顾性队列研究于2020年3月至5月进行,并在法国的三个急性老年病房中进行。包括住院治疗Covid-19感染的年长患者。我们收集了临床,放射性和实验室结果。 (3)结果:九十四名患者住院治疗,包括在最终分析中。平均年龄为85.5岁,55%是女性。六十四(68%)患者确认了Covid-19案,30例(32%)可能。大多数患者依赖于依赖(77%),45%营养不良,并且根据CIRS-G得分(12.3±25.6),均值的平均数量高。住院治疗的主要原因是发烧(30%),呼吸困难(28%)和老年综合征(秋季,谵妄,萎靡)(18%)。随访后,32%呈现急性呼吸衰竭和30%的老年复杂性。脆弱和老年特征与死亡率无关。急性呼吸衰竭(p = 0.03)和淋巴细胞增长(p = 0.02)与死亡率显着相关。 (4)结论:在与Covid-19住院的老年患者中,临床介绍通常是非典型的,并且经常发生并发症。脆弱和老年特征与死亡率无关。

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