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Antibiotic prophylaxis and infectious complications in patients on peritoneal dialysis undergoing lower gastrointestinal endoscopy

机译:患者腹膜透析患者抗生素预防和感染性并发症

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摘要

Peritoneal dialysis (PD) is widely used for the treatment of end-stage renal disease. Patients treated with PD have similar outcomes to those treated with hemodialysis [1]. However, PD-related infections including peritonitis have been reported at 1.66 episodes per patient per year [2]. One possible source of peritonitis is gastrointestinal (GI) endoscopic procedures. In 2005, the International Society for Peritoneal Dialysis (ISPD) published guidelines suggesting antibiotics be given to PD patients prior to colonoscopy [3]. This suggestion was mostly based on expert opinion and a theoretical concern that patients undergoing colonoscopy are at increased risk for enteric peritonitis from bacterial translocation across the bowel wall. While there is no direct evidence to support this theory, case reports have suggested a risk of transient bacteremia associated with colonoscopy.
机译:腹膜透析(PD)广泛用于治疗末期肾病。用PD治疗的患者对血液透析治疗的人进行了类似的结果[1]。然而,每年患者每位患者的1.66发作报告了PD相关的感染,每年均报告每年[2]。一种可能的腹膜炎是胃肠道(GI)内窥镜手术。 2005年,国际腹膜透析学会(ISPD)公布了指导原则,表明在结肠镜检查之前给PD患者提供抗生素[3]。该建议主要是基于专家意见和理论问题,即经接受结肠镜检查的患者对肠道壁的细菌易位的风险增加。虽然没有直接证据来支持这种理论,但案例报告表明存在与结肠镜检查相关的瞬态菌血症的风险。

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