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Emodin Alleviates Severe Acute Pancreatitis-Associated Acute Lung Injury by Inhibiting the Cold-Inducible RNA-Binding Protein (CIRP)-Mediated Activation of the NLRP3/IL-1

机译：大黄素通过抑制NLRP3 / IL-1的冷诱导的RNA结合蛋白（CIRP）介导的激活来减轻严重的急性胰腺炎相关急性肺损伤

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期刊名称 Frontiers in Pharmacology
作者
Qiushi Xu; Mengfei Wang; Haoya Guo; Huanhuan Liu; Guixin Zhang; Caiming Xu; Hailong Chen;
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作者单位

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年(卷),期 2021(-1),-1
年度 2021
页码 -1
总页数 14
原文格式 PDF
正文语种
中图分类药学;
关键词
Severe acute pancreatitis; acute lung injury; emodin; CIRP; NLRP3; CXCL1;

机译：严重的急性胰腺炎;急性肺损伤;大蛋白;CIRP;NLRP3;CXCL1;

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专利

1. Emodin alleviates severe acute pancreatitis-associated acute lung injury by decreasing pre-B-cell colony-enhancing factor expression and promoting polymorphonuclear neutrophil apoptosis [J] . Cui Hongzhang, Li Shu, Xu Caiming, Molecular medicine reports . 2017,第4aPta3期

机译：大黄素通过减少B-Cell菌落增强因子表达和促进多晶核中性粒细胞凋亡，减轻严重的急性胰腺炎相关的急性肺损伤
2. Cold-inducible RNA-binding protein (CIRP) causes sepsis-associated acute lung injury via induction of endoplasmic reticulum stress [J] . Mohammad Moshahid Khan, Weng-Lang Yang, Max Brenner, Scientific reports. . 2017,第1期

机译：冷诱导的RNA结合蛋白（CIRP）通过诱导内质网胁迫导致败血症相关的急性肺损伤
3. Emodin Protects Against Acute Pancreatitis-Associated Lung Injury by Inhibiting NLPR3 Inflammasome Activation via Nrf2/HO-1 Signaling [J] . Zhenming Gao, Jidong Sui, Rong Fan, Drug Design, Development and Therapy . 2020,第1期

机译：通过NRF2 / HO-1信号传导抑制NLPR3炎性激活来保护急性胰腺炎相关肺损伤
4. Activation of nuclear factor-kappa B (NF-kB) in alveolar macrophages and lung tissue of ventilated animals with acute lung injury. [C] . Acta pharmacologica sinica . 2002

机译：急性肺损伤通气动物肺泡巨噬细胞和肺组织中核因子-κB（NF-kB）的活化。
5. Traumatic Brain Injury-Induced Acute Lung Injury: Evidence for Activation and Inhibition of a Neural-Respiratory-Inflammasome Axis [D] . Kerr, Nadine A. 2019

机译：创伤性脑损伤诱导的急性肺损伤：激活和抑制神经呼吸 - 炎症轴的证据
6. Emodin alleviates severe acute pancreatitis-associated acute lung injury by decreasing pre-B-cell colony-enhancing factor expression and promoting polymorphonuclear neutrophil apoptosis [O] . Hongzhang Cui, Shu Li, Caiming Xu, -1

机译：大黄素通过减少前B细胞集落增强因子的表达并促进多形核中性粒细胞凋亡来减轻重症急性胰腺炎相关的急性肺损伤
7. Emodin Alleviates Severe Acute Pancreatitis-Associated Acute Lung Injury by Inhibiting the Cold-Inducible RNA-Binding Protein (CIRP)-Mediated Activation of the NLRP3/IL-1β/CXCL1 Signaling [O] . Qiushi Xu, Mengfei Wang, Haoya Guo, 2021

机译：Emodin通过抑制NLRP3 / IL-1β/ CXCL1信号传导的冷诱导的RNA结合蛋白（CIRP）介导的激活来减轻严重的急性胰腺炎相关急性肺损伤

Emodin Alleviates Severe Acute Pancreatitis-Associated Acute Lung Injury by Inhibiting the Cold-Inducible RNA-Binding Protein (CIRP)-Mediated Activation of the NLRP3/IL-1

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