Peptide signaling without feedback in signal production operates as a true quorum sensing communication system in

摘要

a A communication system, where the response is linearly dependent on bacterial density tracks the bacterial density, however, there is no threshold density at which one could define the quorum. The switchlike transition from no response to max response describes an ideal quorum sensing system where upon reaching a critical concentration the QS response is attained. The less ideal, but anyway non-linearly controlled by the bacterial density, is the graded QS response. b The type of response mode in B. subtilis ComQXPA communication system where the peptide ComX activates the response, which is the transcription of genes encoding the response molecule (RM) surfactin synthethase, is unknown.