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Multi-Method Complex Approach for Hydration Assessment Does Not Detect a Hydration Difference in Hemodialysis versus Peritoneal Dialysis Patient

机译:用于水化评估的多方法复杂方法并未检测血液透析与腹膜透析患者的水化差异

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摘要

Assessment of hydration status is essential in monitoring the effectiveness of renal replacement therapy and is usually based on physical examination. However, comparisons of hydration status achieved with different dialysis methods are not conclusive. We compared the hydration status of patients on chronic hemodialysis (HD, n = 60) and peritoneal dialysis (PD, n = 20) in a comprehensive assessment including physical examination and additional methods. The mean age of the 80 chronically dialyzed patients (53 males, 27 females) was 58.1 ± 13.9 years. The clinical evaluation took into account the presence of peripheral edema, dyspnea, and crackling over the lung fields. Additional tests included lung ultrasound, electrical bioimpedance (performed in 79 patients), impedance cardiography, ultrasound assessment of large abdominal vessels (performed in 79 patients), select echocardiographic parameters (obtained in 78 patients), and serum NT-proBNP concentration. Residual diuresis volume was significantly higher in the PD group. We found no significant differences between the two groups in any other baseline characteristics or in the results of the clinical examination or additional tests. The use of different methods for assessing hydration does not allow differentiation of patients treated with dialysis in terms of the dialysis technique used. Therefore, it seems reasonable to use common algorithms to objectify the hydration status of these patients.
机译:水合状态评估对于监测肾置换疗法的有效性并通常基于体检。然而,用不同透析方法实现的水合状态的比较并不决定。我们将患者的水合状态与慢性血液透析(HD,N = 60)和腹膜透析(PD,N = 20)进行综合评估,包括体检和其他方法。 80例慢性透析患者(53名男性,27名女性)的平均年龄为58.1±13.9岁。临床评估考虑了外周水肿,呼吸困难和裂缝在肺部领域的存在。额外的测试包括肺超声,电气生物阻抗(在79名患者中进行),阻抗心脏造影,大型腹部血管的超声评估(在79名患者中进行),选择超声心动图参数(在78名患者中获得),以及血清NT-PROPNP浓度。 PD组残留的利尿体积显着较高。我们发现两组在任何其他基线特征或临床检查结果中没有显着差异或临床检查或额外测试。使用不同方法进行评估方法不允许在使用的透析技术方面对透析治疗的患者分化。因此,使用常见算法似乎是合理的,以客观地象于这些患者的水合状态。

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