Washed microbiota transplantation for the treatment of recurrent fungal infection in a patient with ulcerative colitis

摘要

To the Editor: Long-term use of antifungals can disrupt the balance of fungal community, making the fungal infection treatments more difficulty and aggravating colitis in patients. The exploration of fecal microbiota transplantation (FMT) in reducing Candida to contain pro-inflammatory immunity induced by gut mycobiota has gained a new appreciation.[1] The new methodology of FMT was recently coined as washed microbiota transplantation (WMT) based on the automatic purification system and washing process, released by the consensus statement from the Fecal Microbiota-standardization Study Group in 2019.[2,3] Here, we report a male patient with recurrent fungal infection who was successfully cured by serial WMTs.