Left atrial appendage amputation using a modified appendage clip: an experimental canine study

摘要

To the Editor: Atrial fibrillation (AF) is one of the most common cardiac arrhythmias observed in the general population. The main cause of stroke associated with AF is the formation of thrombosis in the left atrial appendage (LAA) and falling off from it. More than 90% of cardiogenic thromboses originated from the LAA because the saccate and complex morphology of the LAA induces stasis of blood flow.[1] In the present study, we aimed to evaluate the feasibility and efficacy of mini-invasive thoracotomy implantation of a modified LAA clip (LAAC) in a canine model by general observation, biochemical and histological studies, and echocardiography.