Nanjing consensus on methodology of washed microbiota transplantation

摘要

The methods of fecal microbiota transplantation (FMT) and the related results vary a lot among centers worldwide. Therefore, methodologic standardization can improve the clinical practice and trials about FMT. A panel of 28 experts from 22 hospitals or institutes in 15 cities has contributed to the present consensus on washed microbiota transplantation (WMT).[1] This consensus provides guidance on the methodology of WMT, which is different from that of the manually FMT in recent experts’ consensus or recommendations.[2,3] All experts were assigned, according to their expertise, to the following five groups: Group 1, donor screening; Group 2, washing microbiota protocol, storing, and transport; Group 3, patient preparation; Group 4, delivery decision; Group 5, safety and management. Each statement and the following comment have passed a Delphi process and a face-to-face plenary meeting. The best available evidence was assessed according to the Grading of Recommendations Assessment, Development and Evaluation system.