Critical care for severe coronavirus disease 2019: a population-based study from a province with low case-fatality rate in China

摘要

The coronavirus disease 2019 (COVID-19) pandemic has affected over twenty million people worldwide since its outbreak,[1] in which approximately 19% are expected to progress to severe or critical disease, constituting the high-risk group for death.[2] The reported case-fatality rates among the severe COVID-19 varied a lot across different regions from zero to 61.5%[1,3] and the reason behind remained unclear. Very limited data concerning management of severe cases were reported from low case-fatality areas. In this study, we described the clinical features, multi-strategy management, and respiratory support resources usage for the severe COVID-19 in Sichuan province, where the 28-day case-fatality rate was 0.6% in all patients and 3.7% in severe cases, which was much lower compared with that reported in most of the studies worldwide.