Fine-Needle Aspiration Cytology and Histological Types of Thyroid Cancer in the Elderly: Evaluation of 9070 Patients from a Single Referral Centre

摘要

Elderly patients have a high prevalence of thyroid nodules, and their management should consider the presence of comorbidities, which are frequent in this age group. In this retrospective monocentric study, we analyzed data of more than 13,000 nodules in order to highlight differences between the elderly and the general population in terms of cytological and histological diagnoses. Thyroid nodules in the elderly are more often benign than in younger patients. Nevertheless, in case of malignancy, follicular-derived well-differentiated tumors are almost always diagnosed in younger patients. Instead, elderly patients more often have tumors with aggressive histotypes. In addition, even in presence of well-differentiated tumors, elderly patients present a higher rate of high-risk pathological features.