Graph embeddings on gene ontology annotations for protein–protein interaction prediction

摘要

Illustration of missing and spurious PPI predictions. a The ground-truth PPI graph derived from a real-world PPI dataset where nodes are the proteins and edges represent PPI. b A derived PPI graph, with two PPIs (indicated by the blue dashed edges) removed from a, and is used for missing PPI prediction where the blue dashed edges are missing PPIs. c A derived PPI graph, with two PPIs (indicated by the red bold edges) added to a and is used for spurious PPI prediction where the red bold edges are spurious PPIs