Anti-Coccidial Effect of Rumex Nervosus Leaf Powder on Broiler Chickens Infected with Eimeria Tenella Oocyst

摘要

Eimeria tenella pathogens belong to the Eimeriidae family and the Apicomplexa phylum, which invades the cecal epithelium of birds, resulting in massive injury and economic loss. We evaluated the ameliorative effect of Rumex nervosus (RN) leaf powder against E. tenella-induced coccidiosis in broiler chickens. Chickens infected with E. tenella were treated with 1, 3, and 5 g/kg RN, respectively. Salinomycin sodium (Sacox®), an anti-coccidial agent, was used as a reference drug. Results have shown that RN contains Gallic acid and 13 phytochemicals, which require further investigation in vitro or in vivo to ascertain whether the anti-coccidial activity, if there, is a direct or indirect link to reduce the number of fecal oocysts in the bird. The lesion score and bloody diarrhea were also decreased after infection. Moreover, the coccidial challenge adversely affected (p < 0.05) the performance measurements in the RN- and Sacox-treated groups compared with the uninfected–unmedicated control (NC) group. Interestingly, these parameters were positively affected by natural and synthetic treatments compared with infected–unmedicated control (PC); however, the values were not significant. In conclusion, RN at the highest dose is a promising shrub with a moderate anti-coccidial activity when used to cure avian coccidiosis.