Real-time sensing of MAPK signaling in medulloblastoma cells reveals cellular evasion mechanism counteracting dasatinib blockade of ERK activation during invasion

著录项

• 期刊名称 Neoplasia (New York N.Y.)
• 作者

  Marc Thomas Schönholzer; Jessica Migliavacca; Elena Alvarez; Karthiga Santhana Kumar; Anuja Neve; Alexandre Gries; Min Ma; Michael A. Grotzer; Martin Baumgartner;

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• 作者单位

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• 年(卷),期 2020(22),10
• 年度 2020
• 页码 -1
• 总页数 14
• 原文格式 PDF
• 正文语种
• 中图分类 肿瘤学;
• 关键词

  bFGF; basic fibroblast growth factor; c-Met; cellular mesenchymal epithelial transition factor; EGF; epidermal growth factor; ERK; Extracellular regulated kinase; FDA; food and drug administration; FGFR; fibroblast growth factor receptor; HGF; hepatocyte growth factor; JNK; c-jun N-terminal kinase; MAPK; mitogen-activated protein kinases; MB; medulloblastoma; SHH; sonic hedgehog; SKARS; Synthetic Kinase Activation Relocation Sensor; WST; water soluble tetrazolium salt;