Improvement of the newly developed latex agglutination test (Katex) for diagnosis of visceral lieshmaniasis

摘要

: Different methods are available for diagnosis of visceral leishmaniasis (VL), among them the urine‐based antigen detection assay, latex agglutination test (Katex), is a recently developed one. The main drawback of the test is false‐positive reactivity in some of healthy individuals. The false positivity of the test can be removed by boiling the urine sample for 5 min before testing. In this study an attempt was made to improve Katex by removing unpleasant boiling process, which also decreases field applicability of the test.