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Comparing Methods of Measurement for Detecting Drug‐Induced Changes in the QT Interval: Implications for Thoroughly Conducted ECG Studies

机译：检测QT间隔中药物引起的变化的测量方法比较：对心电图研究进行彻底的启示

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摘要

The aim of this study was to compare the reproducibility and sensitivity of four commonly used methods for QT interval assessment when applied to ECG data obtained after infusion of ibutilide.

机译：这项研究的目的是比较四种常用的QT间期评估方法的重现性和敏感性，该方法适用于输注依布利特后获得的ECG数据。

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期刊名称 Annals of Noninvasive Electrocardiology
作者
Nkechi E. Azie; Gregory Adams; Borje Darpo; Steven F. Francom; Emery C. Polasek; Joy M. Wisser; Joseph C. Fleishaker;
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作者单位

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年(卷),期 2004(9),2
年度 2004
页码 -1
总页数 9
原文格式 PDF
正文语种
中图分类心血管疾病;
关键词
QT interval; QT prolongation; ECG methodology; ibutilide;

机译：QT间期;QT延长;心电图方法学;依布利特;

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专利

1. Comparing QT interval variability of semiautomated and high-precision ECG methodologies in seven thorough QT studies-implications for the power of studies intended for definitive evaluation of a drug's QT effect [J] . Meiser Karin, Jordaan Pierre, Latypova Sasha, Annals of noninvasive electrocardiology: the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc . 2017,第1期

机译：比较半动化和高精度ECG方法的QT间隔变异在七种彻底的QT研究中的影响 - 为试用药物QT效应的明确评估
2. Drug-induced QT prolongation when QT interval is measured in each of the 12 ECG leads in men and women in a thorough QT study. [J] . Gopi Krishna Panicker, Vaibhav Salvi, Dilip R Karnad, Journal of Electrocardiology: An International Publication for the Study of the Electrical Activities of the Heart . 2014,第2期

机译：在一项全面的QT研究中，对男性和女性的12条ECG导线中的每条导线测量QT间隔时，药物引起的QT延长。
3. Drug-induced QT prolongation when QT interval is measured in each of the 12 ECG leads in men and women in a thorough QT study. [J] . Gopi Krishna Panicker, Vaibhav Salvi, Dilip R Karnad, Journal of Electrocardiology: An International Publication for the Study of the Electrical Activities of the Heart . 2014,第2期

机译：在彻底的QT研究中，在12个ECG中的每一个中测量Qt间隔时，药物诱导的QT延长。
4. Effects of Lead Position, Cardiac Rhythm Variation and Drug-induced QT Prolongation on Performance of Machine Learning Methods for ECG Processing [C] . Marat Bogdanov, Salim Baigildin, Aigul Fabarisova, Ural Symposium on Biomedical Engineering, Radioelectronics and Information Technology . 2020

机译：导联位置，心律变化和药物诱导的QT延长对ECG加工机器学习方法性能的影响
5. Potential mechanisms for drug-induced prolongation of QT interval and genesis of torsades de pointes evaluated in the failing rabbit heart. [D] . Kijtawornrat, Anusak. 2007

机译：在衰竭的心脏中评估了药物引起的QT间隔延长和扭转性扭转的潜在机制。
6. Comparing QT interval variability of semiautomated and high‐precision ECG methodologies in seven thorough QT studies—implications for the power of studies intended for definitive evaluation of a drugs QT effect [O] . Karin Meiser, Pierre Jordaan, Sasha Latypova, 2017

机译：在七个详尽的QT研究中比较半自动和高精度ECG方法学的QT区间变异性-旨在明确评估药物QT效果的研究功效
7. New quantitative methods for evaluation of dynamic changes in QT interval on 24 hour Holter ECG recordings: QT interval in idiopathic ventricular fibrillation and long QT syndrome [O] . Sugao, M, Fujiki, A, Sakabe, M, 2006

机译：评估动态心电图24小时QT间隔动态变化的新定量方法：特发性室颤和长期QT综合征的QT间隔

Comparing Methods of Measurement for Detecting Drug‐Induced Changes in the QT Interval: Implications for Thoroughly Conducted ECG Studies

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