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Development of a Novel Anti-Obesity Compound with Inhibiting Properties on the Lipid Accumulation in 3T3-L1 Adipocytes

机译:对3T3-L1脂肪细胞中脂质蓄积具有抑制作用的新型抗肥胖化合物的研制

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摘要

Obesity as a developing global challenge can be characterized by increase in adipocyte number and size arising from adipogenesis. Control of adipogenesis, as a potential strategy, can prevent and manage obesity. So far, the effectiveness of herbal medicine and active ingredients therapies for obesity and metabolic syndrome treatment has been investigated. In this study, a novel combination of berberine, catechin, and capsaicin was developed, and their effect on 3T3-L1 adipocytes was investigated.
机译:肥胖是发展中的全球性挑战,其特征可以在于脂肪形成中脂肪细胞数量和大小的增加。作为潜在策略,控制脂肪生成可以预防和控制肥胖。迄今为止,已经研究了草药和有效成分疗法对肥胖症和代谢综合征的治疗效果。在这项研究中,开发了一种小碱,儿茶素和辣椒素的新型组合,并研究了它们对3T3-L1脂肪细胞的作用。

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