首页> 美国卫生研究院文献>Archives of Medical Science : AMS >MicroRNA-1179 regulates proliferation and chemosensitivity of human ovarian cancer cells by targeting the PTEN-mediated PI3K/AKT signaling pathway

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MicroRNA-1179 regulates proliferation and chemosensitivity of human ovarian cancer cells by targeting the PTEN-mediated PI3K/AKT signaling pathway

机译：MicroRNA-1179通过靶向PTEN介导的PI3K / AKT信号通路来调节人卵巢癌细胞的增殖和化学敏感性

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摘要

Owing to widespread roles of miRs, the dysregulation of their expression in human tissues has been linked with the development of several diseases such as cancer. The study was designed to investigate the role and therapeutic potential of miR-1179 in ovarian cancer.

机译：由于miR的广泛作用，其在人体组织中表达的失调与多种疾病（例如癌症）的发展有关。该研究旨在调查miR-1179在卵巢癌中的作用和治疗潜力。

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期刊名称 Archives of Medical Science : AMS
作者
Zhang Zhihong; Chen Rubin; Lu Liping; Mao Anpeng; Guo Hui; Wu Yanting; Shan Zhenxiu;
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作者单位

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年(卷),期 2020(16),4
年度 2020
页码 -1
总页数 8
原文格式 PDF
正文语种
中图分类基础医学;
关键词
microRNA; apoptosis; miR-1179; ovarian cancer;

机译：microRNA;细胞凋亡;miR-1179;卵巢癌;

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专利

1. miR-214 targets the PTEN-mediated PI3K/Akt signaling pathway and regulates cell proliferation and apoptosis in ovarian cancer [J] . Liu Jing, Chen Weiyan, Zhang Haiyan, Oncology letters . 2017,第5aPta2期

机译：miR-214靶向PTEN介导的PI3K / AKT信号通路，并调节卵巢癌中的细胞增殖和细胞凋亡
2. MiR-200b-5p inhibits proliferation of ovarian cancer cells by targeting ATAD2 and regulating PI3K/AKT signaling pathway [J] . A.-Q. Wang, M. Lv, Y.-H. Xu, European review for medical and pharmacological sciences. . 2020,第19期

机译：miR-200b-5p通过靶向ATAD2和调节PI3K / AKT信号通路来抑制卵巢癌细胞的增殖
3. Thymosin alpha 1 suppresses proliferation and induces apoptosis in breast cancer cells through PTEN-mediated inhibition of PI3K/Akt/mTOR signaling pathway [J] . Guo Yan, Chang Hui, Li Jing, Apoptosis: An international journal on programmed cell death . 2015,第8期

机译：胸腺素α1通过PTEN介导的PI3K / Akt / mTOR信号通路抑制作用抑制乳腺癌细胞的增殖并诱导其凋亡
4. Ang-2 promoting proliferation of SW1116 colon cancer cells through PI3K/Akt pathways [C] . Hong Zhang Ji, Yang Wen Chun, Ping Wang Ai, 2011 International Conference on Human Health and Biomedical Engineering . 2011

机译：Ang-2通过PI3K / Akt途径促进SW1116结肠癌细胞的增殖
5. The multi-targeted receptor tyrosine kinase inhibitor, linifanib (ABT-869), induces apoptosis and inhibits proliferation of leukemia cells through phosphoinositide-3 kinase (PI3K)/AKT-dependent signaling pathways. [D] . Hernandez, Jenny Elizabeth. 2010

机译：多靶点受体酪氨酸激酶抑制剂利尼法尼（ABT-869）通过磷酸肌醇3激酶（PI3K）/ AKT依赖性信号传导途径诱导凋亡并抑制白血病细胞的增殖。
6. miR-214 targets the PTEN-mediated PI3K/Akt signaling pathway and regulates cell proliferation and apoptosis in ovarian cancer [O] . Jing Liu, Weiyan Chen, Haiyan Zhang, -1

机译：miR-214靶向PTEN介导的PI3K / Akt信号通路并调节卵巢癌中的细胞增殖和凋亡
7. MicroRNA-1179 regulates proliferation and chemosensitivity of human ovarian cancer cells by targeting the PTEN-mediated PI3K/AKT signaling pathway [O] . Zhang Zhihong, Chen Rubin, Lu Liping, 2020

机译：MicroRNA-1179通过靶向PTEN介导的PI3K / AKT信号通路来调节人卵巢癌细胞的增殖和化学敏感性

MicroRNA-1179 regulates proliferation and chemosensitivity of human ovarian cancer cells by targeting the PTEN-mediated PI3K/AKT signaling pathway

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