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Bleomycin-Induced Cryptogenic Organizing Pneumonia Manifested as Spontaneous Pneumothorax in a Patient with Classic Seminoma

机译:博莱霉素诱导的隐源性组织性肺炎表现为经典精原细胞瘤患者的自发性气胸。

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摘要

Cryptogenic Organizing Pneumonia (COP) can manifest like a collagen disorder or infectious diseases, or be caused by drug induced toxicity. This paper presents the case of a 24 year-old man diagnosed with classic seminoma, treated with chemotherapy scheme that included bleomycin (accumulated dose, 120 units). The patient was admitted at the hospital due to rapidly-progressing dyspnea and thoracic pain. The diagnostic approach revealed the presence of a spontaneous pneumothorax, while a lung biopsy documented COP. Despite treatment, the patient died from disease progression.
机译:隐源性组织性肺炎(COP)可能像胶原蛋白疾病或传染病一样出现,或者是由药物诱导的毒性引起的。本文介绍了一例诊断为经典精原细胞瘤的24岁男性,接受包括博来霉素(累计剂量120个单位)的化疗方案的治疗。该患者因呼吸困难和胸痛迅速而入院。诊断方法显示存在自发性气胸,而肺活检记录为COP。尽管进行了治疗,该患者仍死于疾病进展。

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