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Point-of-Care Strategies for Detection of Waterborne Pathogens

机译:水性病原体检测的即时战略

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摘要

Waterborne diseases that originated due to pathogen microorganisms are emerging as a serious global health concern. Therefore, rapid, accurate, and specific detection of these microorganisms (i.e., bacteria, viruses, protozoa, and parasitic pathogens) in water resources has become a requirement of water quality assessment. Significant research has been conducted to develop rapid, efficient, scalable, and affordable sensing techniques to detect biological contaminants. State-of-the-art technology-assisted smart sensors have improved features (high sensitivity and very low detection limit) and can perform in a real-time manner. However, there is still a need to promote this area of research, keeping global aspects and demand in mind. Keeping this view, this article was designed carefully and critically to explore sensing technologies developed for the detection of biological contaminants. Advancements using paper-based assays, microfluidic platforms, and lateral flow devices are discussed in this report. The emerging recent trends, mainly point-of-care (POC) technologies, of water safety analysis are also discussed here, along with challenges and future prospective applications of these smart sensing technologies for water health diagnostics.
机译:由病原体微生物引起的水源性疾病正在引起全球严重的健康关注。因此,对水资源中的这些微生物(细菌,病毒,原生动物和寄生性病原体)进行快速,准确和特异性的检测已经成为水质评估的要求。已经进行了大量研究以开发快速,有效,可扩展和负担得起的传感技术来检测生物污染物。最先进的技术辅助智能传感器具有改进的功能(高灵敏度和非常低的检测极限),并且可以实时执行。但是,仍然需要在关注全球和需求的情况下促进这一研究领域。保持这种观点,本文经过精心设计和批判性地探索了为检测生物污染物而开发的传感技术。在此报告中讨论了使用纸质化验,微流体平台和侧向流动装置的进展。本文还讨论了水安全分析的新兴趋势,主要是即时医疗(POC)技术,以及这些智能传感技术在水健康诊断中的挑战和未来的应用前景。

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