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Successful treatment of cholesterol crystal embolism with anti-proprotein convertase subtilisin/kexin type 9 (PCSK9) antibody: a case report

机译：抗前蛋白转化酶枯草杆菌蛋白酶/ kexin 9型（PCSK9）抗体成功治疗胆固醇晶体栓塞：一例报告

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摘要

We report a unique case of renal cholesterol crystal embolism (CCE) induced by carotid artery stenting that was successfully treated with evolocumab, a fully human monoclonal antibody against proprotein convertase subtilisin kexin type 9 (PCSK9).

机译：我们报告了一个独特的案例，该案例由颈动脉支架置入术诱发的肾胆固醇晶体栓塞（CCE）成功地用evolocumab治疗，evolocumab是针对人9型前蛋白转化酶枯草杆菌蛋白酶的完全人类单克隆抗体。

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期刊名称 Renal Failure
作者
Junki Morino; Keiji Hirai; Shohei Kaneko; Saori Minato; Katsunori Yanai; Yuko Mutsuyoshi; Hiroki Ishii; Momoko Matsuyama; Taisuke Kitano; Mitsutoshi Shindo; Akinori Aomatsu; Haruhisa Miyazawa; Kiyonori Ito; Yuichiro Ueda; Susumu Ookawara; Yoshiyuki Morishita;
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作者单位

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年(卷),期 2020(42),1
年度 2020
页码 -1
总页数 6
原文格式 PDF
正文语种
中图分类泌尿科学（泌尿生殖系疾病）;小儿泌尿科学;肾疾病;
关键词
Cholesterol crystal embolism; evolocumab; Anti-PCSK9 antibody;

机译：胆固醇晶体栓塞;evolocumab;抗PCSK9抗体;

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1. Successful treatment of cholesterol crystal embolism with anti-proprotein convertase subtilisin/kexin type 9 (PCSK9) antibody: a case report [J] . Junki Morino, Keiji Hirai, Shohei Kaneko, Renal failure. . 2020,第1期

机译：用抗Proprotine转化酶枯草杆菌蛋白酶/ kexin型9（PCSK9）抗体的成功治疗胆固醇晶体栓塞蛋白酶/ kexin：案例报告
2. Reduction of low density lipoprotein- cholesterol and cardiovascular events with proprotein convertase subtilisin-kexin type 9 (PCSK9) inhibitors and statins: an analysis of FOURIER, SPIRE, and the Cholesterol Treatment Trialists Collaboration [J] . Ference Brian A., Cannon Christopher P., Landmesser Ulf, European Heart Journal: The Journal of the European Society of Cardiology . 2018,第27期

机译：用Proprotein转化酶枯草杆菌蛋白酶-Kexin的低密度脂蛋白 - 胆固醇和心血管事件的减少9（PCSK9）抑制剂和他汀类药物：傅立叶，尖顶和胆固醇治疗试验专题的分析
3. Low-density lipoprotein cholesterol-lowering effects of AMG 145, a monoclonal antibody to proprotein convertase subtilisin/kexin type 9 serine protease in patients with heterozygous familial hypercholesterolemia: The reduction of LDL-C with PCSK9 inhibition in heterozygous familial hypercholesterolemia disorder (RUTHERFORD) randomized trial [J] . RaalF., ScottR., SomaratneR., Circulation: An Official Journal of the American Heart Association . 2012,第20期

机译：AMG 145的低密度脂蛋白胆固醇降低作用，对杂合子家族性高胆固醇血症患者的前蛋白转化酶枯草杆菌蛋白酶/ kexin 9型丝氨酸蛋白酶的单克隆抗体：PCSK9抑制可降低LDL-C对杂合子家族性高胆固醇血症（RUTHERFORD）的影响试用
4. Towards Investigating the Role of Proprotein Convertase Subtilisin/Kexin Family (PCSK/7/9) in Cancer by Using Bioinformatics Motif Detection Technique [C] . Umar Draz, Sana Yasin, Shafiq Hussain, International Bhurban Conference on Applied Sciences and Technologies . 2021

机译：通过使用生物信息学主题检测技术来研究Proprotein转化酶枯草杆菌素/ kexin家族（PCSK / 7/9）的作用
5. Evaluation of the Interaction Between Proprotein Convertase Subtilisin/Kexin Type 9 and Sterol Carrier Protein-2 [D] . Ahranjani, Reza. 2017

机译：评价前蛋白转化酶枯草杆菌蛋白酶/ Kexin 9型与甾醇载体蛋白2的相互作用。
6. Reduction of low density lipoprotein-cholesterol and cardiovascular events with proprotein convertase subtilisin-kexin type 9 (PCSK9) inhibitors and statins: an analysis of FOURIER SPIRE and the Cholesterol Treatment Trialists Collaboration [O] . Brian A Ference, Christopher P Cannon, Ulf Landmesser, -1

机译：前蛋白转化酶枯草杆菌素-kexin 9型（PCSK9）抑制剂和他汀类药物可降低低密度脂蛋白胆固醇和心血管事件：FOURIERSPIRE和胆固醇治疗试验师合作的分析
7. Successful treatment of cholesterol crystal embolism with anti-proprotein convertase subtilisin/kexin type 9 (PCSK9) antibody: a case report [O] . Junki Morino, Keiji Hirai, Shohei Kaneko, 2020

机译：用抗Proprotine转化酶枯草杆菌蛋白酶/ kexin型9（PCSK9）抗体的成功治疗胆固醇晶体栓塞蛋白酶/ kexin：案例报告

Successful treatment of cholesterol crystal embolism with anti-proprotein convertase subtilisin/kexin type 9 (PCSK9) antibody: a case report

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