Polymorphism in Macrophage Migration Inhibitory Factor -173GC in Pediatric Patients with Autoimmune Hepatitis

机译：小儿自身免疫性肝炎巨噬细胞迁移抑制因子-173GC多态性

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Autoimmune hepatitis (AIH) is a chronic disease that may lead to cirrhosis. The immunopathogenesis of AIH is not fully understood and it mainly involves T-cell mediated mechanism. Macrophage migration inhibitory factor (MIF) is a pro-inflammatory cytokine that promotes T cell response and its polymorphism may serve as a severity marker of AIH. No previous study has considered investigating MIF polymorphism in children with AIH.

机译：自身免疫性肝炎（AIH）是一种慢性疾病，可能导致肝硬化。尚未完全了解AIH的免疫发病机制，它主要涉及T细胞介导的机制。巨噬细胞迁移抑制因子（MIF）是一种促炎性细胞因子，可促进T细胞反应，其多态性可作为AIH的严重程度指标。以前没有研究考虑过研究AIH儿童的MIF多态性。

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期刊名称 Pediatric Gastroenterology Hepatology Nutrition
作者
Mona Abdel Latif Alsayed; Shymaa Mohsen Elbeah; Manal M. El-Desoky; Shereen Magdy Elziny; Ahmed Megahed;
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作者单位

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年(卷),期 2020(23),1
年度 2020
页码 -1
总页数 9
原文格式 PDF
正文语种
中图分类儿科学;
关键词
Autoimmune hepatitis; Children; Macrophage migration inhibitory factor; −173 GC polymorphism;

机译：自身免疫性肝炎;儿童;巨噬细胞迁移抑制因子;−173 GC多态性;

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专利

1. A Macrophage Migration Inhibitory Factor Polymorphism Is Associated with Autoimmune Hepatitis Severity in US and Japanese Patients [J] . David N. Assis, Hiroki Takahashi, Lin Leng, Digestive Diseases and Sciences . 2016,第12期

机译：巨噬细胞迁移抑制因子多态性与美国和日本患者的自身免疫性肝炎严重程度有关
2. Macrophage Migration Inhibitory Factor –173GC Variant Might Increase the Risk of Beh?et’s Disease [J] . Nursal A.F., Yigit S., Tural E., Medical principles and practice: international journal of the Kuwait University, Health Science Centre . 2018,第3期

机译：巨噬细胞迁移抑制因子–173GC变异可能会增加贝希特氏病的风险
3. Gene polymorphisms of macrophage migration inhibitory factor affect susceptibility to chronic hepatitis B virus infection in an Iranian cohort [J] . Moudi Bita, Heidari Zahra, Mahmoudzadeh-Sagheb Hamidreza, Microbiology and Immunology . 2016,第6期

机译：巨噬细胞迁移抑制因子的基因多态性影响伊朗人群对慢性乙型肝炎病毒感染的易感性
4. Molecular function of macrophage migration inhibitory factor and a novel therapy for inflammatory bowel disease [C] . Jun Nishihira International Conference on Nutrition and Physical Activity in Aging, Obesity, and Cancer . 2012

机译：巨噬细胞迁移抑制因子的分子函数及炎性肠病的新疗法
5. Macrophage migration inhibitory factor: A study of the effects on the central nervous system microenvironment in experimental autoimmune encephalomyelitis. [D] . Cox, Gina Mavrikis. 2011

机译：巨噬细胞迁移抑制因子：对实验性自身免疫性脑脊髓炎对中枢神经系统微环境影响的研究。
6. Correction: Polymorphism in Macrophage Migration Inhibitory Factor -173GC in Pediatric Patients with Autoimmune Hepatitis [O] . Mona Abdel Latif Alsayed, Shymaa Mohsen Elbeah, Manal M. El-Desoky, 2020

机译：校正：小儿自身免疫性肝炎患者巨噬细胞迁移抑制因子-173GC多态性
7. Polymorphism in Macrophage Migration Inhibitory Factor -173GC in Pediatric Patients with Autoimmune Hepatitis [O] . Mona Abdel Latif Alsayed, Shymaa Mohsen Elbeah, Manal M. El-Desoky, 2020

机译：巨噬细胞迁移抑制因子-173GC在儿科肝炎患者中的多态性

Polymorphism in Macrophage Migration Inhibitory Factor -173GC in Pediatric Patients with Autoimmune Hepatitis

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