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Microbiological Characterization and Clinical Outcomes After Extended-Pulsed Fidaxomicin Treatment for Clostridioides difficile Infection in the EXTEND Study

机译：在EXTEND研究中长期应用非达索霉素治疗艰难梭菌感染的微生物学特征和临床结果

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( ) infection (CDI) is diagnosed using clinical signs and symptoms plus positive laboratory tests. Recurrence of CDI after treatment is common, and coinfection with other enteric pathogens may influence clinical outcomes.

机译：（）感染（CDI）是使用临床体征和症状加上阳性实验室检查来诊断的。治疗后CDI复发很常见，与其他肠道病原体共感染可能会影响临床结果。

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期刊名称 Open Forum Infectious Diseases
作者
Mark H Wilcox; Oliver A Cornely; Benoit Guery; Chris Longshaw; Areti Georgopali; Andreas Karas; Gbenga Kazeem; Jose Alejandro Palacios-Fabrega; Maria J G T Vehreschild;
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作者单位

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年(卷),期 2019(6),11
年度 2019
页码 -1
总页数 7
原文格式 PDF
正文语种
中图分类病毒传染病;
关键词
fidaxomicin; gut microbiota; infection; vancomycin;

机译：非达索星;肠道菌群;感染;万古霉素;

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专利

1. Extended-pulsed fidaxomicin versus vancomycin for Clostridium difficile infection: EXTEND study subgroup analyses [J] . Cornely Oliver A., Vehreschild Maria J. G. T., Adomakoh Nicholas, European journal of clinical microbiology and infectious diseases: Official publication of the European Society of Clinical Microbiology . 2019,第6期

机译：延长脉冲Fidaxomicin与梭菌腹菌感染的万古霉素：延伸研究亚组分析
2. Efficacy and safety of fidaxomicin for the treatment of Clostridioides (Clostridium) difficile infection in a randomized, double-blind, comparative Phase III study in Japan [J] . Mikamo, H.a, Tateda, Journal of infection and chemotherapy: official journal of the Japan Society of Chemotherapy . 2018,第9a10期

机译：Fidaxomicin在日本随机，双盲，比较期III研究中治疗梭霉素（Clostridium）艰难梭菌感染的疗效和安全性
3. Experience With Fidaxomicin as First-Line Treatment for C. difficile Infection (CDI): Clinical Outcomes and Cost-Effectiveness [J] . Planche Tim, Whitney Laura, Ahmad Attiq, The American Journal of Gastroenterology . 2014,第Suppla2期

机译：非达索霉素作为艰难梭菌感染（CDI）一线治疗的经验：临床结果和成本效益
4. The Clinical Outcome of Infections Due to Extended Spectrum β-Lactamase Producing (ESBL) Enterobacteriaceae [C] . Perovic O., Brink A., Richards G., International Congress of Chemotherapy and Infection . 2009

机译：扩展β-内酰胺酶产生（ESBL）肠杆菌的感染临床结果
5. Prediction of Clostridium Difficile Infection Recurrence and Risk-Based Heterogeneity of Treatment Effect of Vnacomycin vs Fidaxomicin. [D] . Alraddadi, Basem. 2013

机译：瓦克霉素与非达霉素的难治性梭状芽胞杆菌感染复发的预测及基于风险的异质性。
6. 1952. Evaluation of Relapse and Reinfection Using Whole-Genome Sequencing of Clostridium difficile Isolates From Elderly Patients With C. difficile Infection (CDI) in the EXTEND Randomized Controlled Comparative Study of Extended-Pulsed Fidaxomicin and Vancomycin for the Treatment of CDI [O] . Mark Wilcox, Oliver A Cornely, Benoit Guery, -1

机译：1952年。在延长的非达索霉素和万古霉素对CDI治疗的EXTEND随机对照比较研究中对来自艰难梭菌感染老年患者（CDI）的艰难梭菌分离株进行全基因组测序评估复发和再感染
7. Pharmacokinetic analysis of an extended-pulsed fidaxomicin regimen for the treatment of Clostridioides (Clostridium) difficile infection in patients aged 60 years and older in the EXTEND randomized controlled trial [O] . Benoit Guery, Areti Georgopali, Andreas Karas, 2020

机译：延长随机对照试验中60岁及以上患者治疗梭肽（Clostridium）艰难梭菌性感染的延长脉冲皮瘤素治疗的药代动力学分析

Microbiological Characterization and Clinical Outcomes After Extended-Pulsed Fidaxomicin Treatment for Clostridioides difficile Infection in the EXTEND Study

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