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The Expression and Prognostic Significance of Claudin-8 and Androgen Receptor in Breast Cancer

机译：Claudin-8和雄激素受体在乳腺癌中的表达及预后意义

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摘要

Claudin-8 (CLDN8) has been identified as an androgen-regulated gene in prostate cancer. However, the role of CLDN8 has not been fully explored in breast cancer. We aimed to explore the expression of CLDN8 and androgen receptor (AR), determine the correlation between CLDN8 and AR, assess the prognostic value of CLDN8 and AR co-expression, and investigate the possible CLDN8 expression molecular mechanism in breast cancer.

机译：Claudin-8（CLDN8）已被确定为前列腺癌中雄激素调节的基因。但是，CLDN8在乳腺癌中的作用尚未得到充分研究。我们旨在探讨CLDN8和雄激素受体（AR）的表达，确定CLDN8和AR之间的相关性，评估CLDN8和AR共表达的预后价值，并探讨CLDN8表达在乳腺癌中的可能分子机制。

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期刊名称 OncoTargets and therapy
作者
Yiqi Zhang; Ang Zheng; Heng Lu; Zining Jin; Ziqi Peng; Feng Jin;
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作者单位

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年(卷),期 2020(13),-1
年度 2020
页码 -1
总页数 12
原文格式 PDF
正文语种
中图分类应用微生物学 ; 肿瘤学 ;
关键词
claudin-8; androgen receptor; breast cancer; prognosis;

机译：claudin-8;雄激素受体;乳腺癌;预后;

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专利

1. The Expression and Prognostic Significance of Claudin-8 and Androgen Receptor in Breast Cancer [J] . Yiqi Zhang, Ang Zheng, Heng Lu, OncoTargets and therapy . 2020 ,第2期

机译：克劳丁-8和雄激素受体在乳腺癌中的表达及预后意义
2. Expression level of androgen receptors in tumor tissue and its prognostic significance in primary operable luminal breast cancer without overexpression of Her2eu in postmenopausal women [J] . Кит Олег Иванович, Шатова Юлиана Сергеевна, Токмаков Василий Васильевич, Kazan Medical Journal . 2019 ,第1期

机译：绝经后女性肿瘤组织中雄激素受体的表达水平及其在原发性可手术管腔型乳腺癌中的表达及预后意义
3. Prognostic significance of androgen receptor expression in invasive breast cancer: transcriptomic and protein expression analysis [J] . Aleskandarany Mohammad A., Abduljabbar Rezvan, Ashankyty Ibraheem, Breast cancer research and treatment. . 2016 ,第2期

机译：浸润性乳腺癌中雄激素受体表达的预后意义：转录组和蛋白质表达分析
4. Estrogen Receptor-Positive Breast Cancer: Traditional Prognostics, Molecular Pathology: A New Breast Cancer Taxonomy and 21st Century Personalized Prognostic and Predictive Assays [C] . Frederick L. Baehner International Symposium on Cancer Metastasis and the Lymphovascular system: Basis for Rational Therapy . 2009

机译：雌激素受体阳性乳腺癌：传统预测，分子病理：新的乳腺癌分类和21世纪个性化预测和预测测定
5. Functional significance of androgen receptor mutations in prostate and breast cancer [D] . Steinkamp, Mara P. 2009

机译：前列腺癌和乳腺癌中雄激素受体突变的功能意义
6. The prognostic significance of combined androgen receptor E-Cadherin Ki67 and CK5/6 expression in patients with triple negative breast cancer [O] . Barbara Adamo, Giuseppina Rosaria Rita Ricciardi, Antonio Ieni, 2017

机译：雄激素受体E-钙黏着蛋白Ki67和CK5 / 6联合表达在三阴性乳腺癌患者中的预后意义
7. Expression level of androgen receptors in tumor tissue and its prognostic significance in primary operable luminal breast cancer without overexpression of Her2/neu in postmenopausal women [O] . O I Kit, Yu S Shatova, V V Tokmakov, 2019

机译：肿瘤组织中雄激素受体的表达水平及其在绝经后妇女的初级可操作腔乳腺癌中的预后显着性

The Expression and Prognostic Significance of Claudin-8 and Androgen Receptor in Breast Cancer

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