Repeated stereotactic radiosurgery for the treatment of relapsed brain metastases: is it time to give up whole-brain radiotherapy?

摘要

Technological progress in radiotherapy (RT) permits the irradiation of brain metastases (BMs) effectively and with limited toxicity. Recently, monoisocentric techniques have been introduced in clinical practice that conjugate traditional stereotactic radiosurgery (SRS) accuracy with the ability to simultaneously irradiate multiple BMs [ ]. This has directly led to a significant reduction in treatment time and cost when compared to the conventional radiation approach, which consists of multiple sessions with dedicated plans for each target volume [ , ].