Analysis of the Occurrence of Major Hemorrhagic Incidents in Patients with Low-Dose Aspirin Usage in Korean Populations – Does Low-Dose Aspirin Really Increase the Risk of Bleeding?

摘要

Aspirin, which has traditionally been used for analgesics and anti-inflammatory drugs, is known to have primary and secondary preventive effects as an antiplatelet agent against cerebrovascular diseases such as myocardial infarction, stroke, and transient cerebral ischemia [ , ]. Low-dose aspirin, however, is known to increase the risk of gastrointestinal and intracranial hemorrhage, but there have been few studies on Korean populations, especially using large-scale data. We wanted to confirm the risk of low-dose aspirin bleeding in real Korean populations. Therefore, we have recently assessed the risk of hemorrhage (extracranial bleeding, such as gastrointestinal hemorrhage, and intracranial bleeding, such as spontaneous intracerebral hemorrhage) in patients who take low doses of aspirin using large-scale data.