Enantioselective Synthesis Enantiomeric Separations and Chiral Recognition

摘要

Chirality is a geometric property associated with the asymmetry of tridimensional features that accompanies our daily life at macroscopic as well as microscopic molecular levels. Chirality is a hallmark of many natural small molecules, and it is intrinsically associated with chiral building blocks as D-sugars and L-amino acids, intervening in chemical procedures of living cells, for example, as enzymes and receptors constituent proteins. Interestingly, free D-amino acids, which are naturally occurring, are important biomarkers with diagnostic value that demonstrate the importance of chiral analyses [ ]. Nevertheless, the importance of chirality is recognized across many related areas as witnessed in wide-ranging fields such as chemistry, physics, biochemistry, material science, pharmacology, and many others ( ).