首页> 美国卫生研究院文献>Journal of Ovarian Research >Correction to: Kallistatin inhibits tumour progression and platinum resistance in high-grade serous ovarian cancer
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Correction to: Kallistatin inhibits tumour progression and platinum resistance in high-grade serous ovarian cancer

机译:校正至:Kallistatin抑制高度浆液性卵巢癌的肿瘤进展和铂耐药性

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摘要

Kallistatin (KAL) inhibited the proliferation of ovarian cancer cells in vitro and in vivo. ( ) The effect of kallistatin on ovarian cancer cell proliferation as measured by MTT assays; A2780 and UWB1.289 cells were transfected stably with PCMV-NC and PCMV-KAL. A2780 and OVCAR3 cells were transfected transiently with kallistatin siRNA. ( ) Colony formation assays were used to measure the effect of kallistatin on A2780, UWB1.289 and OVCAR3 cell growth. ( ) Cell cycle analysis of A2780 and OVCAR3 cells. ( ) UWB1.289 cells stably transfected with PCMV-NC and PCMV-KAL were injected subcutaneously into nude female mice. The tumour weights in the PCMV-KAL group were significantly decreased compared with those in the control group. *  p p
机译:Kallistatin(KAL)在体外和体内均能抑制卵巢癌细胞的增殖。 ()通过MTT分析测定,利他汀对卵巢癌细胞增殖的影响;用PCMV-NC和PCMV-KAL稳定转染A2780和UWB1.289细胞。用Kallistatin siRNA瞬时转染A2780和OVCAR3细胞。 ()用菌落形成测定法来测定kaallistatin对A2780,UWB1.289和OVCAR3细胞生长的影响。 ()A2780和OVCAR3细胞的细胞周期分析。 ()将经PCMV-NC和PCMV-KAL稳定转染的UWB1.289细胞皮下注射到雌性裸鼠中。与对照组相比,PCMV-KAL组的肿瘤重量显着降低。 * p

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