NDRG2 gene expression pattern in ovarian cancer and its specific roles in inhibiting cancer cell proliferation and suppressing cancer cell apoptosis

摘要

NDRG2 mRNA expression and protein levels in tissue samples and cell lines ( and ) NDRG2 mRNA and protein expression was determined in 6 paired non-cancerous and tumor tissues by real-time PCR and Immunoblotting. The expressions of NDRG2 protein in non-cancerous and tumor tissues was detected by IHC assay. and NDRG2 mRNA and protein expression was determined in one normal cell line and three ovarian cancer cell lines, SKOV3, OVCAR-3, and CAOV3 by real-time PCR and Immunoblotting. **