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HUMAN, CERVICAL CANCER-SPECIFIC SUPPRESSOR PROTEIN, POLYNUCLEOTIDE CODING FOR THE PROTEIN, CELL TRANSFORMED WITH THE POLYNUCLEOTIDE AND METHOD OF SUPPRESSING THE PROLIFERATION OF CANCER CELLS USING THE EXPRESSION VECTOR
HUMAN, CERVICAL CANCER-SPECIFIC SUPPRESSOR PROTEIN, POLYNUCLEOTIDE CODING FOR THE PROTEIN, CELL TRANSFORMED WITH THE POLYNUCLEOTIDE AND METHOD OF SUPPRESSING THE PROLIFERATION OF CANCER CELLS USING THE EXPRESSION VECTOR
The present invention provides a human tumor suppressor protein having the amino acid sequence of SEQ ID NO: 2; a polynucleotide encoding the tumor suppressor protein; an expression vector containing the polynucleotide; a microorganism or animal cell transformed with the expression vector; a method for suppressing proliferation of a cancer cell which comprises introducing the expression vector into a cancer cell to induce apoptosis thereof; and a pharmaceutical composition for preventing or treating cancer which comprises a therapeutically effective amount of the polynucleotide and a pharmaceutically acceptable carrier.
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机译:本发明提供了具有SEQ ID NO:2的氨基酸序列的人肿瘤抑制蛋白。编码肿瘤抑制蛋白的多核苷酸;含有多核苷酸的表达载体;用表达载体转化的微生物或动物细胞;一种抑制癌细胞增殖的方法,该方法包括将表达载体引入癌细胞以诱导其凋亡。预防或治疗癌症的药物组合物,其包含治疗有效量的多核苷酸和药学上可接受的载体。
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