Serum histone H3 levels and platelet counts are potential markers for coagulopathy with high risk of death in septic patients: a single-center observational study

摘要

Serum histone H3 levels are correlated with coagulation markers. Correlations between serum histone H3 levels (ng/mL) and coagulation marker levels, including platelet counts (PLT, × 10 /μL), fibrin(ogen) degradation products levels (FDP, μg/mL), thrombin-antithrombin complex levels (TAT, ng/mL), SIRS score, prothrombin time (PT) ratio, and antithrombin activity (AT, %), on ICU day 1 are shown. Spearman’s ρ and values, are also shown. Logarithmic scales are used, except for SIRS score.