Two-Year Integrated Efficacy And Safety Analysis Of Benralizumab In Severe Asthma

机译：贝那珠单抗治疗严重哮喘两年综合疗效和安全性分析

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摘要

Benralizumab is an interleukin-5 receptor alpha–directed cytolytic monoclonal antibody. Treatment with benralizumab significantly reduces exacerbations and improves lung function after 1 year for patients with severe, uncontrolled eosinophilic asthma.

机译：贝那珠单抗是一种白介素5受体α定向的溶细胞单克隆抗体。对于严重，无法控制的嗜酸性粒细胞性哮喘患者，贝那利珠单抗治疗1年后可显着降低病情加重并改善肺功能。

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期刊名称 Journal of Asthma and Allergy
作者
J Mark FitzGerald; Eugene R Bleecker; Arnaud Bourdin; William W Busse; Gary T Ferguson; Laura Brooks; Peter Barker; Ubaldo J Martin;
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作者单位

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年(卷),期 2019(12),-1
年度 2019
页码 -1
总页数 13
原文格式 PDF
正文语种
中图分类
关键词
asthma; benralizumab; clinical features; eosinophilic inflammation; interleukin-5 receptor; safety;

机译：哮喘;贝那珠单抗;临床特征;嗜酸性粒细胞炎症;白介素5受体;安全性;

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专利

1. Two-Year Integrated Efficacy And Safety Analysis Of Benralizumab In Severe Asthma [J] . J Mark FitzGerald, Eugene R Bleecker, Arnaud Bourdin, Journal of Asthma and Allergy . 2019,第3期

机译：患有哮喘患者的两年综合疗效和安全分析
2. Efficacy and safety of treatment with biologicals (benralizumab, dupilumab, mepolizumab, omalizumab and reslizumab) for severe eosinophilic asthma. A systematic review for the EAACI Guidelines ‐ recommendations on the use of biologicals in severe asthma [J] . Allergy . 2020,第5期

机译：生物学（Benralizumab，Dupilumab，Mepolizumab，Omalizumab和Reslizumab）治疗的疗效和安全性对严重的嗜酸性哮喘。对EAACI指南的系统审查 - 关于在严重哮喘中使用生物学的建议
3. Efficacy and safety of treatment with biologicals (benralizumab, dupilumab and omalizumab) for severe allergic asthma: A systematic review for the EAACI Guidelines ‐ recommendations on the use of biologicals in severe asthma [J] . Allergy . 2020,第5期

机译：对生物（Benralizumab，Dupilumab和Omalizumab）治疗的疗效和安全性严重过敏性哮喘：对EAACI指南的系统审查 - 关于使用生物学在严重哮喘中使用的建议
4. Proteomic and informatic approaches in the U-BIOPRED severe asthma project: large-scale MS~E, data mining, topological data analysis, and machine learning [C] . Dominic Burg, Doroteya Staykova, Xian Yang, ASMS Conference on Mass Spectrometry and Allied Topics . 2014

机译：U-Biopred严重哮喘项目中的蛋白质组学和信息方法：大规模MS〜E，数据挖掘，拓扑数据分析和机器学习
5. The Safety and Efficacy of Utilization of High-Frequency Ventilation During Transport of Neonates Suffering from Severe Respiratory Disease [D] . Oddi, Michelle. 2018

机译：高频通风在严重呼吸道疾病中的高频通风中利用的安全性和有效性
6. Efficacy and Safety of Benralizumab for Korean Patients With Severe Uncontrolled Eosinophilic Asthma [O] . Hae-Sim Park, Sang Haak Lee, Sook Young Lee, 2019

机译：贝那珠单抗对韩国严重不受控制的嗜酸性粒细胞性哮喘患者的疗效和安全性
7. Two-year integrated steroid-sparing analysis and safety of benralizumab for severe asthma [O] . Arnaud Bourdin, Dominick Shaw, Andrew Menzies-Gow, 2019

机译：两年的综合类固醇制备分析和Benralizumab的严重哮喘的安全性

Two-Year Integrated Efficacy And Safety Analysis Of Benralizumab In Severe Asthma

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