Differential Expression Pattern of Epithelial Mesenchymal Transition Gens: AXL GAS6 Claudin-1 and Cofilin-1 in Different Stages of Epithelial Ovarian Cancer

摘要

Epithelial ovarian cancer (EOC), is the fatal form of gynecological cancer. Almost 70% of ovarian cancer patients are detected at an advanced stage (III–IV) with metastases. Epithelial‐mesenchymal transition (EMT) is a critical process associated with metastasis. This study investigated the expression levels of AXL, GAS6, Claudin-1, and Cofilin-1, as genes involved in EMT in relation to clinicopathologic features in ovarian cancer patients.