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IL-17A a possible biomarker for the evaluation of treatment response in Trypanosoma cruzi infected children: A 12-months follow-up study in Bolivia

机译：IL-17A可能是评估克鲁斯锥虫感染儿童治疗反应的生物标志物：在玻利维亚进行的为期12个月的随访研究

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BackgroundThe National Program for Chagas disease was implemented in Bolivia in 2006, and it greatly decreased the number of infections through vector control. Subsequently, a treatment regimen of benznidazole (BNZ) was started in seropositive school-age children living in certified vector control areas.

机译：背景技术2006年玻利维亚实施了南美锥虫病国家计划，该计划通过病媒控制大大减少了感染数量。随后，针对居住在经过认证的病媒控制区的血清学阳性的学龄儿童开始了苯并硝唑（BNZ）的治疗方案。

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期刊名称 PLoS Neglected Tropical Diseases
作者
Clara Vásquez Velásquez; Graciela Russomando; Emilio E. Espínola; Zunilda Sanchez; Kota Mochizuki; Yelin Roca; Jimmy Revollo; Angelica Guzman; Benjamín Quiroga; Susana Rios Morgan; Roberto Vargas Ortiz; Alberto Zambrana Ortega; Eida Espinoza; Juan Eiki Nishizawa; Mohamed Gomaa Kamel; Mihoko Kikuchi; Shusaku Mizukami; Kesara Na-Bangchang; Nguyen Tien Huy; Kenji Hirayama;
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年(卷),期 2019(13),9
年度 2019
页码 e0007715
总页数 22
原文格式 PDF
正文语种
中图分类寄生动物、寄生虫学;医学寄生虫学;
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1. IL-17A, a possible biomarker for the evaluation of treatment response in Trypanosoma cruzi infected children A 12-months follow-up study in Bolivia [J] . Clara Vásquez Velásquez, Graciela Russomando, Emilio E. Espínola, PLOS Neglected Tropical Diseases . 2019,第9期

机译：IL-17A，可能是评估克鲁氏锥虫感染儿童治疗反应的生物标志物玻利维亚的12个月跟踪研究
2. Polymerase chain reaction detection and serologic follow-up after treatment with benznidazole in Bolivian children infected with a natural mixture of Trypanosoma cruzi I and II. [J] . Flores Chavez M, Bosseno MF, Bastrenta B, The American Journal of Tropical Medicine and Hygiene . 2006,第3期

机译：在感染了克鲁斯锥虫I和II天然混合物的玻利维亚儿童中，用苯并咪唑治疗后的聚合酶链反应检测和血清学随访。
3. Benznidazole treatment in chronic children infected with Trypanosoma cruzi: Serological and molecular follow-up of patients and identification of Discrete Typing Units [J] . RumiM.M.M., PérezBrandánC., GilJ.F., Acta tropica: Journal of Biomedical Sciences . 2013,第1期

机译：苯并硝唑治疗克氏锥虫的慢性儿童：患者的血清学和分子随访及离散分型单位的确定
4. Effect of TGF-beta and TNF-alpha treatment in Trypanosoma cruzi-infected cardiomyocytes: new insights on Chagas' disease extracellular matrix regulation [C] . Calvet C.M, Oliveira, F.O.R., International Congress of Parasitology . 2010

机译：TGF-β和TNF-α治疗在脑瘤瘤瘤瘤感染心肌细胞中的影响：对黏磁疾病细胞外基质调节的新见解
5. Design, synthesis, and biological evaluation of molecules of medicinal interest: Inhibitors of mammalian and Trypanosoma cruzi protein farnesyltransferase and Trypanosoma cruzi lanosterol-14-alpha-demethylase. [D] . Lockman, Jeffrey William. 2003

机译：设计，合成和具有药用价值的分子的生物学评估：哺乳动物和克鲁斯锥虫蛋白法尼基转移酶和克鲁斯锥虫羊毛甾醇14-α-脱甲基酶的抑制剂。
6. Comparative evaluation of short-term biomarker response to treatment for growth hormone deficiency in Chinese children with growth hormone deficiency born small for or appropriate for gestational age: a randomized phase IV open-label study [O] . Wenli Lu, Shuixian Shen, Xiaoping Luo, 2013

机译：中国出生年龄不大或适合胎龄的生长激素缺乏症儿童对生长激素缺乏症治疗的短期生物标志物反应的比较评估：一项随机的IV期开放标签研究
7. IL-17A, a possible biomarker for the evaluation of treatment response in Trypanosoma cruzi infected children: A 12-months follow-up study in Bolivia [O] . Clara Vásquez Velásquez, Graciela Russomando, Emilio E. Espínola, 2019

机译：IL-17A，一种用于评估触发瘤Cruzi感染儿童治疗反应的可能生物标志物：玻利维亚的12个月后续研究
8. Tissue-Reacting Immunoglobulins in Rhesus Monkeys Infected with Trypanosoma cruzi: A Follow-Up Study [R] . Szarfman, A., Gerecht, D., Draper, C. C., 1980

机译：感染克氏锥虫的恒河猴组织反应免疫球蛋白：随访研究

IL-17A a possible biomarker for the evaluation of treatment response in Trypanosoma cruzi infected children: A 12-months follow-up study in Bolivia

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