首页> 美国卫生研究院文献>Heliyon >Functional and histological evaluation of bone marrow stem cell-derived exosomes therapy on the submandibular salivary gland of diabetic Albino rats through TGFβ/ Smad3 signaling pathway

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Functional and histological evaluation of bone marrow stem cell-derived exosomes therapy on the submandibular salivary gland of diabetic Albino rats through TGFβ/ Smad3 signaling pathway

机译：TGFβ/ Smad3信号通路对糖尿病白化病大鼠颌下唾液腺的骨髓干细胞源性外泌体治疗的功能和组织学评价

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摘要

To prevail over diabetes mellitus and its numerous complications, researchers are seeking new therapies. Exosomes are natural cargo of functional proteins and can be used as a therapeutic delivery of these molecules.

机译：为了战胜糖尿病及其众多并发症，研究人员正在寻求新的疗法。外泌体是功能蛋白的天然产物，可以用作这些分子的治疗性递送。

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期刊名称 Heliyon
作者
Nermeen AbuBakr; Tahany Haggag; Dina Sabry; Zeinab A. Salem;
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作者单位

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年(卷),期 2020(6),4
年度 2020
页码 -1
总页数 9
原文格式 PDF
正文语种
中图分类
关键词
Biological sciences; Cell biology; Biochemistry; Molecular biology; Cancer research; Endocrinology; Organ system; Developmental biology; Pathophysiology; Diabetes mellitus; Salivary gland dysfunction; TGβ/Smad3 signaling; Bone marrow stem cell-derived exosomes;

机译：生物科学;细胞生物学;生物化学;分子生物学;癌症研究;内分泌学;器官系统;发育生物学;病理生理学;糖尿病;唾液腺功能障碍;TGβ/ Smad3信号传导;骨髓干细胞衍生的外来体;

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专利

1. Human bone marrow mesenchymal stem cell-derived exosomes stimulate cutaneous wound healing mediates through TGF-β/Smad signaling pathway [J] . Tiechao Jiang, Zhongyu Wang, Ji Sun Stem Cell Research & Therapy . 2020,第1期

机译：人骨髓间充质干细胞衍生的外泌体通过TGF-β/ Smad信号通路刺激皮肤伤口愈合介质
2. Protective effect of bone marrow mesenchymal stem cell-derived exosomes against the reproductive toxicity of cyclophosphamide is associated with the p38MAPK/ERK and AKT signaling pathways [J] . Xiao-Bin Guo, Jia-Wen Zhai, Hui Xia, Asian journal of andrology . 2021,第4期

机译：骨髓间充质干细胞衍生出外泌体对环磷酰胺的繁殖毒性的保护作用与P38MAPK / ERK和AKT信号通路有关
3. Protective effect of bone marrow mesenchymal stem cell-derived exosomes against the reproductive toxicity of cyclophosphamide is associated with the p38MAPK/ERK and AKT signaling pathways [J] . Xiao-Bin Guo, Cun-Dong Liu, Qi-Zhao Zhou, 亚洲男性学杂志（英文版） . 2021,第004期
4. Biofunctionalization of titanium surface with nano-sawtooth structure regulates rat bone marrow mesenchymal stem cells behavior [C] . Lianyi Xu, Wenjie Zhang World biomaterials congress . 2012

机译：具有纳米锯齿结构的钛表面的生物功能调节调节大鼠骨髓间充质干细胞的行为
5. Certain physiological and biochemical studies on submaxillary and parotid salivary glands of normal and diabetic male albino rats [D] . Kishore, Poorna. 1994

机译：正常和糖尿病雄性白化病大鼠颌下和腮腺唾液腺的某些生理生化研究
6. Human bone marrow mesenchymal stem cell-derived exosomes stimulate cutaneous wound healing mediates through TGF-β/Smad signaling pathway [O] . Tiechao Jiang, Zhongyu Wang, Ji Sun 2020

机译：人骨髓间充质干细胞来源的外泌体刺激皮肤伤口愈合通过TGF-β/ Smad信号通路介导
7. Functional and histological evaluation of bone marrow stem cell-derived exosomes therapy on the submandibular salivary gland of diabetic Albino rats through TGFβ/ Smad3 signaling pathway [O] . Nermeen AbuBakr, Tahany Haggag, Dina Sabry, 2020

机译：TGFβ/ Smad3信号通路骨髓干细胞源性对糖尿病白化大鼠颌下唾液腺疗法治疗的功能和组织学评价

Functional and histological evaluation of bone marrow stem cell-derived exosomes therapy on the submandibular salivary gland of diabetic Albino rats through TGFβ/ Smad3 signaling pathway

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