Bacteria increase host micronutrient availability: mechanisms revealed by studies in C. elegans

摘要

. - as a host-microbe model to study the impact of dietary and bacterial micronutrients on host health. acquires micronutrients primarily through the ingestion of but can also uptake dietary micronutrients directly from the growth media. Like all bacteria, synthesizes some micronutrients de novo and uptakes other micronutrients, or their precursors, from its environment. Little is known about how bacteria interact with dietary micronutrients in the provision of micronutrients to the host. In this model system, the supply of micronutrients to can be controlled: genetic and pharmacological methods can be used to target specific pathways in both and and the growth media can be chemically defined