Role of interleukin-23 in the development of nonallergic eosinophilic inflammation in a murine model of asthma

摘要

Experimental protocol. Airway resistance at doses of 50 and 100 mg/mL methacholine (MCh). Inflammatory cells in bronchoalveolar lavage fluid (eosinophils are magnified). IL-13-producing or IL-5-producing type 2 innate lymphoid cells (CD45+Lin− ICOS+) in lung homogenate. IL-17A-producing type 3 innate lymphoid cells (CD45+Lin− CD25+) in lung homogenate. , IL-13-producing or IL-17A-producing CD4+ T cells in lung homogenate. IL-33 and TSLP levels in lung homogenate. *  P #  ##