Can the AGE/RAGE/ERK signalling pathway and the epithelial-to-mesenchymal transition interact in the pathogenesis of chronic rhinosinusitis with nasal polyps?

摘要

Contributions: AV, study design, coordination and manuscript drafting; SP, FC, performing IHC and quantitative analyses; AC, CF performing Western blot analyses; GDM, LA, EI, provided the surgical specimens; RS, study supervision, critical manuscript revision. All the authors have read and approved the final version of the manuscript and agreed to be accountable for all aspects of the work.