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Dataset on the mass spectrometry-based proteomic profiling of the kidney from wild type and the dystrophic mdx-4cv mouse model of X-linked muscular dystrophy

机译:基于质谱的野生型肾脏和X连锁肌营养不良症的营养不良mdx-4cv小鼠模型的蛋白质组学数据集

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摘要

The proteomic data presented in this article provide supporting information to the related research article “Proteomic and cell biological profiling of the renal phenotype of the mouse model of Duchenne muscular dystrophy” (Dowling et al., 2019) [1]. This article supplies additional datasets on protein species with increased versus decreased concentration in the kidney from the dystrophic mouse, as well as tables with mass spectrometrically identified kidney marker proteins that exhibit characteristic tissue distributions, subcellular localizations and physiological functions. Information is provided on the underlying multi-consensus protein listings from the proteomic screening of both wild type and mouse kidneys. The data article provides comprehensive information on the systematic and mass spectrometric identification of the mouse kidney proteome.
机译:本文提供的蛋白质组学数据为相关研究文章“ Duchenne肌营养不良症小鼠模型的肾脏表型的蛋白质组学和细胞生物学概况分析”提供了支持性信息(Dowling等,2019)[1]。本文提供了有关营养不良型小鼠肾脏中浓度升高或降低的蛋白质种类的其他数据集,以及质谱鉴定的肾脏标志物蛋白的表格,这些蛋白质具有特征性的组织分布,亚细胞定位和生理功能。从野生型和小鼠肾脏的蛋白质组学筛选中提供了有关潜在的多共识蛋白清单的信息。数据文章提供了有关小鼠肾脏蛋白质组的系统和质谱鉴定的全面信息。

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